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Study identifier: NCT06819891 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

Condition: Moderately to Severely Active Crohns Disease  ·  Sponsor: Hoffmann-La Roche

PhasePhase 3
Planned participants425
Who can joinAll sexes, 16 Years to 80 Years
Healthy volunteersNo

About this study

This Phase III, multicenter, double-blind, placebo-controlled study will evaluate the efficacy and safety of induction therapy with Afimkibart (also known as RO7790121) in participants with moderately to severely active Crohn's disease (CD).

This description comes directly from the study's public registry record.

Talk to the study team

Reference Study ID Number: GA45332 https://forpatients.roche.com/ No attachments to email below.  ·  888-662-6728 (U.S. and Canada)  ·  global-roche-genentech-trials@gene.com

Fastest response: use the inquiry form. https://www.gene.com/contact-us/submit-medical-inquiry

Always discuss trial participation with your own doctor first.

Locations (187)

Sun City Clinical ResearchGlendale, Arizona, United StatesRecruiting
Om Research LLCLancaster, California, United StatesRecruiting
Hoag Memorial Hospital Presbyterian;Hoag Center for Research and EducationNewport Beach, California, United StatesRecruiting
Empire Clinical ResearchPomona, California, United StatesWithdrawn
Stanford Medicine Outpatient CenterRedwood City, California, United StatesRecruiting
Clinical Applications Laboratories, Inc.San Diego, California, United StatesRecruiting
Amicis Research CenterSanta Clarita, California, United StatesRecruiting
Peak Gastroenterology AssociatesColorado Springs, Colorado, United StatesRecruiting
J&A Clinical ResearchDoral, Florida, United StatesRecruiting
Auzmer ResearchLakeland, Florida, United StatesRecruiting
Galenus Group IncLehigh Acres, Florida, United StatesRecruiting
Homestead Associates in Research, Inc.Miami, Florida, United StatesRecruiting

+ 175 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06819891