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Study identifier: NCT06818851 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

The Effects of Henagliflozin on Glucose Fluctuation and Immunosenescence in Type 2 Diabetes Patients on Insulin Therapy

Condition: Diabetes Mellitus, Type 2  ·  Sponsor: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

PhasePhase 4
Planned participants64
Who can joinAll sexes, 50 Years to 70 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if SGLT2 inhibitor Henggliflozin works to improve glucose variability in type 2 diabetes and if Henggliflozin can benefit immunosenescence. The main questions it aims to answer are: Does Henggliflozin as an add on treatment works to improve blood glucose fluctuation in type 2 diabetes? Does Henggliflozin has extra benefits like improve immunosenescence beyond hypoglycemic effects? Researchers will compare Henggliflozin to a placebo to see if Henggliflozin can improve glucose variability and immunosenescence. Participants will: Take Henggliflozin or a placebo every day for 16 weeks. Receive weekly follow-up calls to guide them in adjusting their insulin doses. Return for an on-site visit at 4 weeks and 16 weeks. Take a continuous glucose monitoring (CGM) for 7 days at the Visit 1 and at the end of the study.

This description comes directly from the study's public registry record.

Talk to the study team

Hongmei Zhang  ·  +8613636347760  ·  spicygirlss@126.com

Always discuss trial participation with your own doctor first.

Locations (1)

Shanghai Jiaotong University School of Medicine, Xinhua HospitalShanghai, Shanghai Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06818851