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Study identifier: NCT06818266 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Efficacy and Safety of Tocilizumab for Acute Chest Syndrome Treatment in Patients With Sickle Cell Disease

Condition: Sickle Cell Disease · Acute Chest Syndrome  ·  Sponsor: Assistance Publique - Hôpitaux de Paris

PhasePhase 3
Planned participants130
Who can joinAll sexes, 2 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to determine whether a single infusion of tocilizumab is effective in reducing the time to successful weaning from both supplemental oxygen and any respiratory support, in pediatric and adult patients with sickle cell disease (SCD) during acute chest syndrome (ACS).

This description comes directly from the study's public registry record.

Talk to the study team

Slimane ALLALI, MD, PhD  ·  01 44 49 48 96  ·  slimane.allali@aphp.fr

Aminata TRAORE, Project advisor  ·  aminata.traore@aphp.fr

Always discuss trial participation with your own doctor first.

Locations (1)

Department of General Pediatrics and Sickle Cell Center, Necker-Enfants malades HospitalParis, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT06818266