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Study identifier: NCT06816927 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Trial of Glioblastoma Immunotherapy Advancement With Nivolumab and Relatlimab

Condition: Newly Diagnosed Glioblastoma  ·  Sponsor: Duke University

PhasePhase 2
Planned participants92
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

GIANT is an open-label, multi-center, randomized, perioperative (neoadjuvant followed by adjuvant), phase 2 trial with a safety lead-in phase to investigate the feasibility, safety and tolerability, and establish the biological activity of nivolumab with or without relatlimab in patients with isocitrate dehydrogenase (IDH) wildtype newly diagnosed glioblastoma (ndGBM).

This description comes directly from the study's public registry record.

Talk to the study team

Mustafa Khasraw  ·  9196845301  ·  mustafa.khasraw@duke.edu

Monika Anand  ·  7326818838  ·  monika.anand@duke.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Duke UniversityDurham, North Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06816927