Condition: Critical Care · Oxygen Therapy · Mechanical Ventilation · Sponsor: Jian-Xin Zhou
Spontaneous breathing trials (SBT) are essential for assessing extubation tolerance, yet optimal approaches are debated. High-flow nasal oxygen offers benefits like precise oxygen delivery, flow-related positive end-expiratory pressure generation and improved lung function. While high-flow tracheal oxygen can also be used as an SBT method, it has reduced physiological effects due to bypassing the upper airway with a more open circuit. To enhance this limitation, investigators developed a modified high-flow tracheal oxygen tube with a smaller expiratory end diameter to increase expiratory resistance and airway pressure. This is a prospective randomized crossover study that aims to compare the physiological effects of standard and modified high-flow tracheal oxygen versus T-piece during SBT.
This description comes directly from the study's public registry record.
Jian-Xin Zhou, MD, PhD · 8610 6392 6666 · zhoujx.cn@icloud.com
Shan-Shan Xu, MD · 8618501219133 · 1004496285@qq.com
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| Beijing Shijitan Hospital | Beijing, Beijing Municipality, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06816706