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Study identifier: NCT06815588 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Improving the Outcomes of Children With Tuberculosis Through Innovative Diagnostics and Treatment Monitoring

Condition: Tuberculosis  ·  Sponsor: Research Center Borstel

PhaseN/A
Planned participants100
Who can joinAll sexes, 0 Years to 14 Years
Healthy volunteersYes

About this study

This study aims at identifying and evaluating novel diagnostic methods for children evaluated for respiratory tuberculosis. The investigators will use alternative samples like stool, urine, and masks to diagnose children with respiratory tuberculosis. Once diagnosed, the investigators will use target next generation sequencing to determine if the bacillus is resistant to any of the drugs used for treatment. Additionally, children initiated under TB treatment will be followed-up during treatment to measure blood biomarkers for outcome prediction. Finally, spirometry will be performed longitudinally until 3 months after the end of treatment to assess the lung capacity of children treated for respiratory TB. All children initiated on TB treatment will fill in a quality of life questionnaire.

This description comes directly from the study's public registry record.

Talk to the study team

Anca Vasiliu, MD, PhD  ·  +33652727749  ·  avasiliu@fz-borstel.de

Dragos Baiceanu, MD  ·  dragos_baiceanu@yahoo.com

Always discuss trial participation with your own doctor first.

Locations (1)

Marius Nasta Institute of PneumologyBucharest, BUC, RomaniaRecruiting

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Source record: clinicaltrials.gov/study/NCT06815588