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Study identifier: NCT06814626 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Role of Nutritional Intervention for the Treatment of Sarcopenia in Cirrhotic Patients With Refractory Ascites Candidate to Transjugular Intrahepatic Portosystemic Shunt Placement and Identification of Prognostic Factors Related to Clinical Outcome

Condition: Liver Cirrhosis · Refractory Ascites in Patients With Cirrhosis · Sarcopenia in Liver Cirrhosis  ·  Sponsor: The Mediterranean Institute for Transplantation and Advanced Specialized Therapies

PhasePhase 3
Planned participants72
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

The hypothesis is that in patients with cirrhosis and refractory ascites candidate to TIPS, and sarcopenia (identified by a PMA ≤16 cm² at the level of L3), who are at high-risk of 6-month mortality after TIPS placement, a post-TIPS 12 weeks nutritional intervention is associated with improved post-TIPS prognosis. The primary objective is to evaluate the effect of a post-TIPS 12 weeks nutritional intervention on liver transplant-free six-month survival in sarcopenic candidates to TIPS for refractory ascites in cirrhosis.

This description comes directly from the study's public registry record.

Talk to the study team

Angelo Luca, Radiologist  ·  +39 0912192468  ·  aluca@ismett.edu

Monica Rizzo, Study Coordinator  ·  +39 0912192692  ·  morizzo@ismett.edu

Always discuss trial participation with your own doctor first.

Locations (2)

IRCCS ISMETT - Istituto Mediterraneo per i Trapianti e le Terapie ad Alta SpecializzazionePalermo, ItalyRecruiting
University Clinic for Visceral Surgery and Medicine, InselspitalBern, SwitzerlandRecruiting

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Source record: clinicaltrials.gov/study/NCT06814626