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Study identifier: NCT06812104 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Phase I Clinical Trial of KK2845 in Patients With Relapsed or Refractory Acute Myeloid Leukemia and Other Hematologic Malignancies.

Condition: Relapsed or Refractory AML and Other Hematologic Malignancies  ·  Sponsor: Kyowa Kirin Co., Ltd.

PhasePhase 1
Planned participants156
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is the first in human study of KK2845. This clinical trial consists of Part 1 (Dose Escalation) and Part 2 (Backfill). For patients with relapsed or refractory acute myeloid leukemia (AML) and other Hematologic Malignancies, in Part 1, the tolerability of KK2845 will be evaluated to determine the maximum tolerated dose (MTD). In Part 2, additional data will be collected by administering KK2845 at dose levels for which tolerability has been confirmed.

This description comes directly from the study's public registry record.

Talk to the study team

Masayoshi Noshiro  ·  +81-90-2488-4889  ·  masayoshi.noshiro.kj@kyowakirin.com

Always discuss trial participation with your own doctor first.

Locations (17)

Kameda General HospitalKamogawa, Chiba, JapanRecruiting
University of Fukui HospitalYoshida, Fukui, JapanRecruiting
Kurume University HospitalKurume, Fukuoka, JapanRecruiting
Hokkaido University HospitalSapporo, Hokkaido, JapanRecruiting
Kansai Medical University HospitalHirakata, Osaka, JapanRecruiting
Dokkyo Medical University HospitalMibu, Tochigi, JapanRecruiting
Japanese Red Cross Musashino HospitalMusashino, Tokyo, JapanRecruiting
Kyushu University HospitalFukuoka, JapanRecruiting
Fukushima Medical University HospitalFukushima, JapanRecruiting
Kanazawa University HospitalKanazawa, JapanRecruiting
Japanese Red Cross Nagasaki Genbaku HospitalNagasaki, JapanRecruiting
Okayama University HospitalOkayama, JapanRecruiting

+ 5 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06812104