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Study identifier: NCT06811896 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Adapting a Stress Management Intervention to Reduce Cardiovascular Disease Risk

Condition: Stress · Blood Pressure · Cardiovascular Diseases (CVD)  ·  Sponsor: University of Alabama at Birmingham

PhaseNA
Planned participants48
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

Women living with HIV have 2-4x higher risk for cardiovascular disease compared to women without HIV, with women living with HIV in the Southern US being particularly at risk. While an increased prevalence of traditional risk factors (e.g., hypertension, diabetes, and obesity) partially explain this risk, evidence suggests that increased exposure to structural and social stressors (e.g., poverty, discrimination, and stigma) among women living with HIV in the South negatively contribute to cardiovascular disease disparities through their impact on stress. The Stress Management and Resiliency Training (SMART) program is an effective, evidence-based intervention proven to improve resiliency to environmental stressors and reduce the physiologic responses to stress which contribute to cardiovascular disease. While the SMART program has demonstrated efficacy in a wide range of populations and settings, it has not been designed for or tested among women living with HIV in the South, where unique cultural and faith-based context may diminish the uptake and value of the intervention to mitigate cardiovascular disease risk. The purpose of this study is to adapt the evidence-based SMART program in consideration of the needs and contexts of women living with HIV in the Southern US and pilot the adapted intervention to establish the feasibility, acceptability, and preliminary impact of the adapted intervention to reduce stress and mitigate cardiovascular disease risk among this population…

This description comes directly from the study's public registry record.

Talk to the study team

Jenni Wise, PhD, MSN  ·  2059969459  ·  jmwise@uab.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Alabama at BirminghamBirmingham, Alabama, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06811896