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Study identifier: NCT06810167 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Assessing Tenapanor as a Treatment of CF-related Constipation.

Condition: Cystic Fibrosis · Constipation  ·  Sponsor: Massachusetts General Hospital

PhasePhase 3
Planned participants25
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

Tenapanor is the newest FDA-approved drug for IBS with constipation (IBS-C). This study seeks to understand tenapanor as a treatment for cystic fibrosis-related constipation (CFrC) in CF patients. Participants will ingest one 50 mg tablet of tenapanor, twice daily, for a 4-week treatment period. They will also complete three questionnaires, the PAC-SYM, PAC-QoL, and IBS-SSS, and daily diaries to characterize GI symptom burden and spontaneous bowel movement (SBM) frequency.

This description comes directly from the study's public registry record.

Talk to the study team

Chloe Butzel, BA  ·  6176437088  ·  cbutzel@mgh.harvard.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Massachusetts General HospitalBoston, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06810167