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Study identifier: NCT06807619 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study of Sotorasib in People With Brain Tumors

Condition: Brain Tumor  ·  Sponsor: Memorial Sloan Kettering Cancer Center

PhasePhase 1
Planned participants16
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The researchers are doing this study to find out how effective sotorasib is at getting into KRAS G12C+ brain tumors. The researchers will also find out whether sotorasib is a safe and effective treatment for people undergoing surgical resection of KRAS G12C+ metastatic brain tumors, and do tests that show how the body absorbs, distributes, and gets rid of sotorasib.

This description comes directly from the study's public registry record.

Talk to the study team

Nelson Moss, MD  ·  212-639-7075  ·  mossn@mskcc.org

Cameron Brennan, MD  ·  212-639-8268

Always discuss trial participation with your own doctor first.

Locations (7)

Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities)Basking Ridge, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Monmouth (Limited Protocol Activities)Middletown, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Commack (Limited Protocol Activities)Commack, New York, United StatesRecruiting
Memorial Sloan Kettering Suffolk- Commack (Limited Protocol Activities)Commack, New York, United StatesRecruiting
Memorial Sloan Kettering West Harrison (Limited Protocol Activities)Harrison, New York, United StatesRecruiting
Memorial Sloan Kettering Cancer Center (All Protocol Activities)New York, New York, United StatesRecruiting
Memorial Sloan Kettering Nassau (Limited Protocol Activities)Uniondale, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06807619