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Study identifier: NCT06806813 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Italian Anderson Fabry Disease Cardiovascular Registry

Condition: Fabry Disease  ·  Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna

PhaseN/A
Planned participants800
Who can joinAll sexes, 2 Years to no upper limit
Healthy volunteersNo

About this study

The RICMAF Study is an observational, multicenter, non-pharmacological study conducted in Italy. Although Anderson-Fabry Disease (AFD) is rare, it is likely underdiagnosed due to its nonspecific symptoms, leading to delays in proper treatment. The RICMAF Study aims to improve understanding of AFD, especially its cardiac manifestations, which are a major cause of mortality. By gathering data from a large, nationwide patient registry, this study seeks to answer key questions about AFD's clinical course and improve patient outcomes. The primary goals of the RICMAF Study are: * To analyze the clinical profile, prevalence, and incidence of AFD, along with patients' family history and disease progression. * To identify early markers of cardiac involvement and predictors of cardiovascular complications to personalize care. * To investigate the relationship between genetic mutations, clinical presentation, and prognosis. * To find early indicators of organ damage through laboratory and imaging tests. All patients diagnosed with AFD following international guidelines are eligible.

This description comes directly from the study's public registry record.

Talk to the study team

Elena Biagini, MD, PhD  ·  +39051214483  ·  elena.biagini@aosp.bo.it

Silvia Palmieri, M. Sc.  ·  +39051214483  ·  silvia.palmieri@aosp.bo.it

Always discuss trial participation with your own doctor first.

Locations (54)

ASL 2 Chieti - Ospedale Policlinico SS. AnnunziataChieti, Abruzzo/Chieti, ItalyNot Yet Recruiting
Azienda Ospedaliera Regionale S.CarloPotenza, Basilicata/Potenza, ItalyNot Yet Recruiting
AORN "Sant'Anna e San Sebastiano" di CasertaCaserta, Caserta, ItalyNot Yet Recruiting
Azienda Ospedaliero - Universitaria "Mater DominiCatanzaro, Catanzaro, ItalyNot Yet Recruiting
Azienda Ospedaliera di Cosenza Università della CalabriaCosenza, Cosenza, ItalyNot Yet Recruiting
IRCCS Azienda Ospedaliero-Universitaria di BolognaBologna, EmiliaRomagna/Bologna, ItalyRecruiting
IRCCS Ospedale Policlinico San MartinoGenova, Genova, ItalyNot Yet Recruiting
ASST Papa Giovanni XXIIIBergamo, Lombardia/Bergamo, ItalyRecruiting
U.O.Cardiologia Spetali Civili 1Brescia, Lombardia/Brescia, ItalyNot Yet Recruiting
IRCCS Ospedale Maggiore Policlinico di MilanoMilan, Lombardia/Milano, ItalyNot Yet Recruiting
IRCCS San Gerardo dei Tintori - S.C. Nefrologia, Monza - Università di Milano BicoccaMilan, Lombardia/Milano, ItalyNot Yet Recruiting
Centro Cardiologico MonzinoMilan, Lombardia/Milano, ItalyRecruiting

+ 42 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06806813