● Recruiting

Predicting clinicAL outcoMes During First-line CDK4/6 Inhibitors Plus Endocrine Therapy in Patients With Advanced Hormone REceptor-poSitive HER2-negative Breast Cancer: the Retrospective-prospective Multicenter Italian PALMARES-2 Study

Condition: Breast Adenocarcinoma · Breast Cancer Stage IV · Breast Cancer, Metastatic · Sponsor: Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

PhaseN/A

Planned participants3500

Who can joinAll sexes, 18 Years to no upper limit

Healthy volunteersNo

About this study

PALMARES-2 is a retrospective/prospective, observational, multicenter, population-based study, aiming at providing real-world evidences on HR+/HER2- aBC patients treated with first-line CDK4/6i plus ET. The present study has the objective to collect data coming from different sources, i.e. RWD, medical images and biological samples, from patients treated with CDK4/6i as first-line of therapy for HR+/HER2- aBC. In consideration of the complexity of data collected and different objectives of the study, this master protocol foresees different sub-studies, which encompasses different methodologies for data collection, data extraction and analyses.

This description comes directly from the study's public registry record.

Talk to the study team

Claudio Vernieri, M.D., Ph.D. · +390223903066 · claudio.vernieri@istitutotumori.mi.it

Always discuss trial participation with your own doctor first.

Locations (24)

Centro di Riferimento Oncologico IRCCS	Aviano, Italy	Recruiting
Azienda Socio Sanitaria Territoriale degli Spedali Civili	Brescia, Italy	Recruiting
Humanitas Istituto Clinico Catanese	Catania, Italy	Recruiting
ASST Lariana - Ospedale Sant'Anna	Como, Italy	Recruiting
ASST Ospedale Maggiore	Cremona, Italy	Recruiting
Azienda Ospedaliero Universitaria Careggi	Florence, Italy	Recruiting
Ospedale San Martino	Genova, Italy	Recruiting
Istituto Tumori della Romagna IRST IRCCS	Meldola, Italy	Recruiting
Fondazione IRCCS Ca' Granda Ospedale Maggiore	Milan, Italy	Recruiting
IEO Istituto Europeo di Oncologia	Milan, Italy	Recruiting
IRCCS Ospedale San Raffaele	Milan, Italy	Recruiting
Ospedale ASST Fatebenefratelli Sacco	Milan, Italy	Recruiting

+ 12 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06805812