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Study identifier: NCT06805253 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Left Ventricular Reverse Remodeling Evaluation After Surgical Correction of Aortic Regurgitation

Condition: Aortic Valve Regurgitation · Mitral Valve Regurgitation · Left Ventricle Dilated  ·  Sponsor: Petrovsky National Research Centre of Surgery

PhaseN/A
Planned participants120
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Investigators assume that surgical correction approach to functional mitral regurgitation during intervention for chronic aortic regurgitation in patients with severe enlargement of the left heart chambers influences reverse remodeling of the left ventricle (LV) in the postoperative period. It is suggested that functional mitral regurgitation (MR) provides supra-physiological left ventricle volume overload and this fact plays positive role in early-stage post-operative left ventricle volume and function recovery. LV volume, systolic and diastolic function will be monitored with echocardiography (EchoCG) along with life quality in patients with different grades of functional mitral regurgitation secondary to severe chronic aortic insufficiency after surgical treatment of aortic regurgitation.

This description comes directly from the study's public registry record.

Talk to the study team

Eduard Charchyan, professor  ·  +79262174114  ·  charchmed@yahoo.com

Andrei Bulynin  ·  +79081339584  ·  bandrew@inbox.ru

Always discuss trial participation with your own doctor first.

Locations (2)

Petrovsky National Research Center of SurgeryMoscow, RussiaRecruiting
Voronezh Regional Clinical Hospital No. 1Voronezh, RussiaRecruiting

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Source record: clinicaltrials.gov/study/NCT06805253