● Recruiting

Standard-of-Care Reduced-Intensity Conditioning (RIC) With 200 Versus 400 cGy of Total Body Irradiation (TBI) in Patients With Acute Leukemia Undergoing First Allogeneic Blood or Marrow Transplantation (BMT)

Condition: Acute Leukemia · Acute Lymphoblastic Lymphoma · Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

PhaseNA

Planned participants160

Who can joinAll sexes, N/A to no upper limit

Healthy volunteersNo

About this study

This is a randomized phase II trial of standard-of-care reduced-intensity conditioning (RIC) with 200 versus 400 cGy of total body irradiation (TBI) in patients with acute leukemia undergoing first allogeneic blood or marrow Transplantation (BMT). The primary objective is to compare the rates of graft-versus-host disease-free and relapse-free survival (GRFS) between patients in the two cohorts.

This description comes directly from the study's public registry record.

Talk to the study team

Jonathan Webster, MD · 410-614-9106 · jwebst17@jhmi.edu

Preston Clairborne, MD · 4109558893 · jclaibo8@jh.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Baltimore, Maryland, United States

Recruiting

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Source record: clinicaltrials.gov/study/NCT06803745