Condition: Small Bowel Obstruction · Sponsor: Nantes University Hospital
Small Bowel Obstruction (SBO) is a frequent pathology in the emergency department (ED). Diagnosis is currently based on abdominal CT scan (CT). Moreover, CT is warranted to determine the therapeutic strategy in patients with SBO which could include medical treatment; surgical intervention or both. However, CT is associated with drawbacks such as radiation exposure, increased cost and ED length-of-stay. In a prospective observational study, a SBO was excluded by CT in 45% \[95%CI: 37-53\] of patients. There is, thus, a need for improving the appropriateness of CT-scan for suspected SBO. A recent meta-analysis showed that Point of care ultrasound (POCUS) had a good diagnostic accuracy (sensitivity 83% \[95%CI 71.7%-90.4%\]), specificity 93% \[95%CI 55.3%-99.3%\]). Another meta-analysis found rather similar results (sensitivity 83% \[(95% CI 89.0% to 94.7%\], specificity 96,6% \[95% CI 88.4% to 99.1%\]). In order to improve the negative predictive value of POCUS for its implementation as a rule-out strategy, CHU of Nantes emergency unit studied the combination of POCUS with Gestalt pre-test probability of SBO determined by the emergency physician. This SBO probability classified the patients as low, moderate or high risk of SBO. In patients with low or moderate Gestalt probability, CHU of Nantes emergency unit found that this combined strategy had a sensitivity of 100% \[95% CI: 88-100\] and NPV 100% \[92-100%\]. By (i) focusing on patients with a low or moderate Gestalt cli…
This description comes directly from the study's public registry record.
Philippe LE CONTE Professor LE CONTE, Professor · 0240083934 · philippe.leconte@chu-nantes.fr
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| Chu Clermont-Ferrand Hopital Gabriel Montpied | Clermont-Ferrand, France, France | Recruiting |
| Ghem Groupe Hospitalier Eaubonne Montmorency Simone Veil | Eaubonne, France, France | Recruiting |
| CHD Vendée | La Roche-sur-Yon, France, France | Recruiting |
| CHD Vendée, Luçon | Luçon, France, France | Recruiting |
| Ap-Hm Hopital La Timone | Marseille, France, France | Recruiting |
| Hôpital Nord | Marseille, France, France | Withdrawn |
| Ghsif Groupe Hospitalier Sud Ile de Franc _ Ch Melun | Melun, France, France | Recruiting |
| CHD Vendée, Montaigu | Montaigu, France, France | Recruiting |
| CHU Nantes | Nantes, France, France | Recruiting |
| Le Confluent | Nantes, France, France | Recruiting |
| CHU CAREMEAU - Nimes | Nîmes, France, France | Recruiting |
| AP-HP Est Parisien _ ST-ANTOINE | Paris, France, France | Recruiting |
+ 6 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06803628