← Eichor
Study identifier: NCT06802315 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Intensity Modulated Total Marrow Irradiation in Fully Human Leukocyte Antigen (HLA)-Matched and Partially-HLA Mismatched Allogeneic Transplantation Patients With High-Risk Acute Myeloid Leukemia (AML), Chronic Myeloid Leukemia (CML), and Myelodysplastic Syndrome (MDS)

Condition: Acute Myeloid Leukemia, Relapsed, Adult · Acute Myeloid Leukemia Refractory · Chronic Myeloid Leukemia - Accelerated Phase  ·  Sponsor: University of Illinois at Chicago

PhasePhase 2
Planned participants38
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

The study is a Phase II clinical trial. Patients will receive intensity-modulated total marrow irradiation (TMI) at a dose of 9 Gray (Gy) with standard myeloablative fludarabine intravenous (IV) and targeted busulfan (FluBu4) conditioning prior to allogeneic hematopoietic stem cell transplant (HSCT). Graft-versus-host disease (GVHD) prophylaxis will include Cyclophosphamide on Day +3 and +4, tacrolimus, and mycophenolate mofetil.

This description comes directly from the study's public registry record.

Talk to the study team

Matias Sanchez, MD  ·  (312) 413-4260  ·  matiass@uic.edu

Marisol Vega, MPH  ·  (312) 413-5035  ·  vegam35@uic.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Illinois Cancer CenterChicago, Illinois, United StatesRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT06802315