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Study identifier: NCT06801899 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

ToPanc Trial: Survival After Total Versus Partial Pancreaticoduodenectomy for Adenocarcinoma of the Pancreatic Head, Distal Cholangiocarcinoma, and Ampullary Cancer

Condition: Pancreatic Cancer  ·  Sponsor: Insel Gruppe AG, University Hospital Bern

PhaseNA
Planned participants170
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if total removal of the pancreas is a preferable alternative to partial removal in patients with cancer of the pancreatic head who are at high risk of pancreatic leakage. The main question it aims to answer is: Does total pancreas removal improve survival without reducing quality of life compared to partial removal? The only study specific procedures are the collection of 2 blood samples (7.5ml for each time point, preoperatively and during the hospitalisation) and the completion of the questionnaires.

This description comes directly from the study's public registry record.

Talk to the study team

Anna S Wenning, MD, PhD  ·  +41 (0)31 632 71 41  ·  annasilvia.wenning@insel.ch

Nadine Uebersax  ·  +41 (0)31 684 33 69  ·  nadine.uebersax@unibe.ch

Always discuss trial participation with your own doctor first.

Locations (10)

Department of General, Visceral and Transplantation Surgery, University Hospital MünsterMünster, GermanyRecruiting
Department of General and Visceral Surgery, University Hospital UlmUlm, GermanyNot Yet Recruiting
Department of General and Visceral Surgery, Kantonsspital AarauAarau, SwitzerlandRecruiting
Department of Surgery, Kantonsspital BadenBaden, SwitzerlandRecruiting
Department of Visceral Surgery, University Hospital BaselBasel, SwitzerlandRecruiting
Inselspital, Bern University HospitalBern, SwitzerlandRecruiting
Department of Visceral Surgery, University Hospital GenevaGeneva, SwitzerlandRecruiting
Department of General, Visceral, Endocrine and Transplantation Surgery, Kantonsspital St. GallenSankt Gallen, SwitzerlandRecruiting
Department of Surgery, Stadtspital Triemli ZürichZurich, SwitzerlandRecruiting
Department of Surgery and Transplantation, University Hospital ZürichZurich, SwitzerlandRecruiting

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Source record: clinicaltrials.gov/study/NCT06801899