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Study identifier: NCT06799247 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Investigating an mRNA CAR T-cell Therapy, Known as Descartes-08, as a Potential Approach to Treat Myasthenia Gravis

Condition: Myasthaenia Gravis  ·  Sponsor: Cartesian Therapeutics

PhasePhase 3
Planned participants100
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The AURORA Study is evaluating the safety, tolerability, and efficacy of an investigational mRNA CAR T-cell therapy known as Descartes-08 in adults with acetylcholine receptor autoantibody -positive generalized myasthenia gravis. Part 1 of the study will last around 6 months. For eligible participants, Part 2 will last around 8 months.

This description comes directly from the study's public registry record.

Talk to the study team

Cartesian Clinical Trials  ·  617-231-8102  ·  trials@cartesiantx.com

Always discuss trial participation with your own doctor first.

Locations (34)

A40Tucson, Arizona, United StatesRecruiting
A13Carlsbad, California, United StatesRecruiting
A46Los Angeles, California, United StatesRecruiting
A14Orange, California, United StatesRecruiting
A21Aurora, Colorado, United StatesRecruiting
A50Washington D.C., District of Columbia, United StatesRecruiting
A48Maitland, Florida, United StatesRecruiting
A10Tampa, Florida, United StatesRecruiting
A53O'Fallon, Illinois, United StatesRecruiting
A20Fairway, Kansas, United StatesRecruiting
A16Lexington, Kentucky, United StatesRecruiting
A38Boston, Massachusetts, United StatesRecruiting

+ 22 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06799247