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Study identifier: NCT06799065 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer

Condition: Advanced Solid Tumors · Breast Cancer Recurrent · Ovarian Cancer  ·  Sponsor: Accent Therapeutics

PhasePhase 1
Planned participants90
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this study is to identify a safe and tolerated dose of the orally administered KIF18A inhibitor ATX-295. In addition, this study will evaluate the pharmacokinetics, pharmacodynamics and preliminary antitumor activity of ATX-295 in patients with advanced solid tumors and ovarian cancer.

This description comes directly from the study's public registry record.

Talk to the study team

Priya Rajaratnam  ·  339) 970-7383  ·  clinicaltrials@accenttx.com

Always discuss trial participation with your own doctor first.

Locations (6)

Florida Cancer SpecialistsSarasota, Florida, United StatesRecruiting
Karmanos Cancer InstituteDetroit, Michigan, United StatesRecruiting
SCRI Oncology PartnersNashville, Tennessee, United StatesRecruiting
MD Anderson Cancer CenterHouston, Texas, United StatesRecruiting
NEXT OncologySan Antonio, Texas, United StatesRecruiting
NEXT VirginiaFairfax, Virginia, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06799065