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Study identifier: NCT06794775 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

SWE-NEO: Swedish NeoAdjuvant Trial Comparing Monotherapy to Combined Immunotherapy in Resectable Stage III Melanoma

Condition: Malignant Melanoma Stage III  ·  Sponsor: Hildur Helgadottir

PhasePhase 3
Planned participants128
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

At present two studies (SWOG S1801 and NADINA) have demonstrated superiority when using neoadjuvant treatment compared to adjuvant treatment only, but no studies have compared PD-1 monotherapy (SWOG 1801 regimen) to the PD-1/CTLA-4 combination (NADINA regimen) therapy. The SWE-NEO study aims to compare these two regimens, where the PD-1/CTLA-4 combination is potentially more effective, but also associated with more side effects.

This description comes directly from the study's public registry record.

Talk to the study team

Hildur Helgadottir, MD, PhD  ·  +46 8-123 734 15  ·  hildur.helgadottir@regionstockholm.se

Roger Olofsson Bagge, Professor  ·  +46313421000  ·  roger.olofsson.bagge@gu.se

Always discuss trial participation with your own doctor first.

Locations (3)

Sahlgrenska University HospitalGothenburg, SwedenRecruiting
Skane University HospitalLund, SwedenRecruiting
Karolinska University HospitalStockholm, SwedenRecruiting

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Source record: clinicaltrials.gov/study/NCT06794775