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Study identifier: NCT06792552 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Phase I Study of SIM0505 in Participants With Advanced Solid Tumors

Condition: Advanced Solid Tumors · Platinum Resistant Ovarian Cancer · Fallopian Tube Cancer  ·  Sponsor: NextCure, Inc.

PhasePhase 1
Planned participants738
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is an open-label, multicenter phase 1 study to evaluate the safety, Tolerability, Pharmacokinetics and Preliminary Antitumor Activity of SIM0505 in Adult Participants with Advanced Solid Tumors

This description comes directly from the study's public registry record.

Talk to the study team

Udayan Guha, PhD, MD  ·  301-919-4218  ·  NCClin@nextcure.com

Siyuan Qian  ·  Siyuan.Qian@zaiming.com

Always discuss trial participation with your own doctor first.

Locations (17)

Sarah Cannon Research Institute (SCRI) - Lake NonaOrlando, Florida, United StatesActive Not Recruiting
Emory Winship Cancer InstituteAtlanta, Georgia, United StatesActive Not Recruiting
University Medical Center of New Orleans LSU-LCMC Health Cancer CenterNew Orleans, Louisiana, United StatesActive Not Recruiting
Dana-Farber Cancer InstituteBoston, Massachusetts, United StatesActive Not Recruiting
Hackensack University Medical CenterHackensack, New Jersey, United StatesActive Not Recruiting
Roswell Park Cancer InstituteBuffalo, New York, United StatesActive Not Recruiting
Icahn School of Medicine at Mount SinaiNew York, New York, United StatesActive Not Recruiting
Sarah Cannon Research Institute (SCRI) - NashvilleNashville, Tennessee, United StatesActive Not Recruiting
UT Health San Antonio - Mays Cancer CenterSan Antonio, Texas, United StatesActive Not Recruiting
The first medical center of PLA general hospitalBeijing, Beijing Municipality, ChinaRecruiting
Liaoning Cancer Hospital & InstituteShenyang, China, ChinaNot Yet Recruiting
The Fourth Hospital of Hebei Medical University (Heibei Tumor Hospital)Shijiazhuang, China, ChinaNot Yet Recruiting

+ 5 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06792552