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Study identifier: NCT06790537 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Efficacy of Pregabalin for Diabetic Pruritus - A Randomized Controlled Study.

Condition: Diabetic Pruritus · Efficacy of Pregabalin in Controlling Diabetic Pruritus Severity  ·  Sponsor: Post Graduate Institute of Medical Education and Research, Chandigarh

PhasePhase 4
Planned participants46
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Brief Summary: The goal of this randomized controlled study is to learn if pregabalin combined with emollients can reduce pruritus (itching) in people with Type 2 Diabetes Mellitus. The main questions it aims to answer are: Does pregabalin combined with emollients reduce pruritus severity compared to a placebo combined with emollients? What is the impact of pregabalin on the quality of life of participants suffering from diabetic pruritus? we will compare pregabalin plus emollient to a placebo plus emollient to see if pregabalin works better for reducing pruritus. Participants will: Receive either pregabalin 75 mg daily along with emollient therapy or a placebo along with emollient therapy. Visit the clinic at weeks 4, 8, and 12 for follow-up assessments, including: Pruritus severity using the Visual Analog Scale (VAS) and 5-D Itch Scale. Patient Global Impression of Change (PGIC) to measure overall improvement. This study will help determine if pregabalin, a drug used for neuropathic pain, can be an effective treatment for pruritus in people with diabetes.

This description comes directly from the study's public registry record.

Talk to the study team

KARTHIK N Dr, MBBS DNB General medicine  ·  +91 9492115369  ·  nalam.karthik8788@gmail.com

Ashu Rastogi, DM Endocrinology  ·  9781001046  ·  ashuendo@gmail.com

Always discuss trial participation with your own doctor first.

Locations (2)

Department of Endocrinology , PGIMER, ChandigarhChandigarh, Chandigarh, IndiaNot Yet Recruiting
Department of Endocrinology , PGIMER, ChandigarhChandigarh, Chandigarh, IndiaRecruiting

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Source record: clinicaltrials.gov/study/NCT06790537