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Study identifier: NCT06789198 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Peptide Vaccine for Fibrolamellar Hepatocellular Carcinoma Patients and Other Tumor Entities Carrying the Driver Fusion DNAJB1-PRKACA

Condition: Fibrolamellar Hepatocellular Carcinoma (FLC)  ·  Sponsor: University Hospital Tuebingen

PhasePhase 1
Planned participants20
Who can joinAll sexes, 12 Years to no upper limit
Healthy volunteersNo

About this study

The aim of this clinical trial is to evaluate the immunogenicity along with safety and toxicity as well as first efficacy of a DNAJB1-PRKACA fusion transcript-based peptide vaccine (Fusion-VAC-XS15) in patients with FL-HCC or other cancer entities carrying the DNAJB1-PRKACA fusion transcript as adjuvant treatment

This description comes directly from the study's public registry record.

Talk to the study team

Juliane Walz, Prof. Dr.  ·  +49 707129  ·  kketi@med.uni-tuebingen.de

Helmut Salih, Prof. Dr.  ·  kketi@med.uni-tuebingen.de

Always discuss trial participation with your own doctor first.

Locations (2)

University Hospital TuebingenTübingen, GermanyRecruiting
Universitätsklinikum Tübingen, Kinderheilkunde ITübingen, GermanyNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06789198