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Study identifier: NCT06789029 Synced from ClinicalTrials.gov · July 28, 2026
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The Effect of Dexamethasone Administration Route and Local Anesthetic Concentration on Pain, Inflammatory Response, and Neuromonitoring in Children Undergoing Scoliosis Correction

Condition: Scoliosis Idiopathic Adolescent  ·  Sponsor: Poznan University of Medical Sciences

PhasePhase 4
Planned participants60
Who can joinAll sexes, 10 Years to 18 Years
Healthy volunteersNo

About this study

Scoliosis correction surgery in children is a complex procedure with significant risks, including postoperative pain, inflammatory response, and potential neurological complications. Effective pain control and minimizing inflammation are critical for faster recovery and improved patient outcomes. Dexamethasone is commonly used as an adjuvant in regional anesthesia due to its anti-inflammatory effects and ability to prolong analgesia. However, limited research exists on the optimal route of dexamethasone administration (intravenous vs. perineural) and the best local anesthetic concentration for pain management, inflammatory response, and neuromonitoring during surgery. This study aims to compare the effects of different dexamethasone administration routes and local anesthetic concentrations on postoperative pain, inflammation (NLR, PLR), and neuromonitoring in pediatric scoliosis surgery. Results may improve regional anesthesia protocols, enhance patient safety, and offer valuable insights for clinical practice.

This description comes directly from the study's public registry record.

Talk to the study team

Malgorzata Reysner, M.D. Ph.D.  ·  +48608762068  ·  mdomagalska@ump.edu.pl

Always discuss trial participation with your own doctor first.

Locations (1)

Poznan University of Medical SciencesPoznan, PolandRecruiting

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Source record: clinicaltrials.gov/study/NCT06789029