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Study identifier: NCT06787911 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Donafenib Combined With Anti-PD-1 Antibody for Neoadjuvant Therapy in Locally Advanced Thyroid Cancer

Condition: Thyroid Cancer  ·  Sponsor: Yu Wang

PhasePhase 2
Planned participants14
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

This study is a single-arm intervention study. Locally advanced differentiated thyroid carcinoma patients receive neoadjuvant therapy with Donafenib and PD-1 antibody Sintilimab and those who can undergo surgery after neoadjuvant therapy receive surgical treatment. The aim of the study is to evaluate the efficacy and safety of Donafenib combined with PD-1 antibody in neoadjuvant therapy of locally advanced thyroid cancer.

This description comes directly from the study's public registry record.

Talk to the study team

Yu Wang  ·  +86 21 6417 5590  ·  neck130@sina.com

Always discuss trial participation with your own doctor first.

Locations (1)

Fudan University Shanghai Cancer CenterShanghai, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06787911