← Eichor
Study identifier: NCT06787612 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer

Condition: Ovarian Cancer · Fallopian Tube Cancer · Primary Peritoneal Cancer  ·  Sponsor: Regeneron Pharmaceuticals

PhasePhase 2
Planned participants220
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is researching an experimental drug called ubamatamab, also referred to as "study drug". The study is focused on patients who have advanced ovarian cancer. The aim of the study is to see how safe, tolerable, and effective the study drug is on its own and in combination with other anti-cancer drugs (bevacizumab, cemiplimab, fianlimab and a standard chemotherapy drug, pegylated liposomal doxorubicin \[PLD\]), referred to as "combination drugs'. The study is looking at several other research questions, including: * What side effects may happen from taking the study drug and its experimental combinations * How much study drug and fianlimab is in the blood at different times * Whether the body makes antibodies against the study drug (which could make the drug less effective or could lead to side effects) and its combinations

This description comes directly from the study's public registry record.

Talk to the study team

Clinical Trials Administrator  ·  844-734-6643  ·  clinicaltrials@regeneron.com

Always discuss trial participation with your own doctor first.

Locations (54)

The University of Alabama at BirminghamBirmingham, Alabama, United StatesRecruiting
UC San Diego HealthLa Jolla, California, United StatesRecruiting
Cedars Sinai Medical CenterLos Angeles, California, United StatesRecruiting
Mayo Clinic JacksonvilleJacksonville, Florida, United StatesRecruiting
University of Miami Sylvester Comprehensive Cancer CenterMiami, Florida, United StatesRecruiting
Advent Health Cancer InstituteOrlando, Florida, United StatesRecruiting
Tampa General Hospital Cancer InstituteTampa, Florida, United StatesRecruiting
University of ChicagoChicago, Illinois, United StatesRecruiting
The University of Kansas Cancer CenterWestwood, Kansas, United StatesRecruiting
Norton Cancer Institute, St. Matthews ClinicLouisville, Kentucky, United StatesRecruiting
Massachusetts General HospitalBoston, Massachusetts, United StatesRecruiting
Karmanos Cancer InstituteDetroit, Michigan, United StatesRecruiting

+ 42 more locations — full list on the registry record.

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT06787612