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Study identifier: NCT06785571 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

The Evaluation of the Effectiveness and Safety of Nalbuphine Hydrochloride Injection for Analgesia in ICU Patients: A Multicenter, Randomized, Single-blinded, Parallel, Two-step Trial

Condition: Respiratory Insufficiency  ·  Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

PhasePhase 2/Phase 3
Planned participants204
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

The analgesic effect of nalbuphine hydrochloride injection will be evaluated in a multicenter, randomized, single-blind, parallel, positive-controlled approach in two steps: step 1, to explore the optimal dosage of nalbuphine hydrochloride injection with 2 experimental arms and 1 positive control and step 2, to evaluate the effectiveness and safety of nalbuphine hydrochloride injection in mechanically ventilated ICU patients at a dosage determined in step 1 with the same positive control.

This description comes directly from the study's public registry record.

Talk to the study team

you shang  ·  02785351606  ·  you_shanghust@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

Wuhan Union HospitalWuhan, Hubei, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06785571