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Study identifier: NCT06784778 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Observational Study of Patients With Advanced Melanoma (Skin Cancer) to Assess if IOpener®-Melanoma Test Can Predict Response to Immunotherapy.

Condition: Melanoma Metastatic · Melanoma, Skin · Melanoma Stage III or IV  ·  Sponsor: Pamgene International B.V.

PhaseN/A
Planned participants196
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this observational study is to assess whether the IOpener® melanoma test can assist treating physicians in deciding which therapy is most suitable for patients with skin cancer (advanced cutaneous melanoma). For this purpose it is evaluated how well the IOpener-melanoma test can predict the result of cancer treatment in the treatment groups (standard of care anti-PD1 mono-therapy and standard of care anti-PD1 + anti-CTLA-4 therapy). Participants will be asked to provide blood sample for analysis using IOpener®-melanoma test. Patients will receive regular medical care, the test results will not be used to make any treatment decisions. The patients will visit the clinic for treatment administration and clinical evaluation as part of their regular medical care.

This description comes directly from the study's public registry record.

Talk to the study team

Project Leader Clinical Trials  ·  + 31 (0) 73 615 80 71  ·  dvdheuvel@pamgene.com

Always discuss trial participation with your own doctor first.

Locations (3)

Universitätsklinikum TübingenTübingen, Baden-Wurttemberg, GermanyRecruiting
Heidelberg University HospitalHeidelberg, GermanyRecruiting
LMU KlinikumMünchen, GermanyRecruiting

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Source record: clinicaltrials.gov/study/NCT06784778