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Study identifier: NCT06782932 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Comparing Neoadjuvant/Adjuvant GVAX vs a mKRASvax Given With Anti-PD-1 and Anti-CD137 for Surgically Resectable Pancreatic Cancer

Condition: Pancreatic Cancer  ·  Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

PhasePhase 1/Phase 2
Planned participants38
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to determine the optimal dose of AGEN2373 that is safe when given in combination with balstilimab and Pancreatic GVAX Whole Cell Vaccine and evaluate the safety and clinical activity of balstilimab and AGEN2373 in combination with GVAX (Arm 1) or mKRASvax (Arm 2) in surgically resectable pancreatic adenocarcinoma.

This description comes directly from the study's public registry record.

Talk to the study team

Colleen Apostol, RN  ·  410-614-3644  ·  GIClinicalTrials@jhmi.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Johns Hopkins Sidney Kimmel Comprehensive Cancer CenterBaltimore, Maryland, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06782932