Condition: Fecal Microbiota Transplantation · Orthotopic Liver Transplantation · Multi-drug Resistant Bacteria · Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna
The increasing emergence and spread of MDRB represents a major public health problem, with higher mortality in patients experiencing infections. Cirrhotic patients listed for OLT and after OLT are at high risk of MDRB colonization or infection due to the large use of broad-spectrum antibiotics in the post-transplant setting. Therefore, effective decolonization strategies in this particular setting are urgently needed. The investigators hypothesize that heterologous FMT can reduce infections rates in the pre-and post- OLT setting by MDRB decolonization and restoration of a more physiological microbiome.
This description comes directly from the study's public registry record.
Giovanni Barbara, MD · +390512144103 · giovanni.barbara@unibo.it
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| IRCCS Azienda Ospedaliero-Universitaria di Bologna | Bologna, Italy | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06782880