Condition: Aortic Regurgitation · Mitral Regurgitation · Aortic Stenosis · Sponsor: The Cleveland Clinic
This project aims to validate sex-specific biologic signatures associated with aortic valve disease developed in a large multicenter CMR registry, using unsupervised phenomapping. The aim to use standard and advanced CMR techniques (MRF, DTI, chemical exchange transfer, and radiomics analysis) is to determine advanced CMR predictors of reverse remodeling following aortic valve surgery and develop sex-specific thresholds for risk. Infrastructure developed by this study will enable development of an innovative, scalable, sex-specific precision medicine cardiovascular imaging pipeline to determine overall risk and treatment response.
This description comes directly from the study's public registry record.
Deborah Kwon, MD · 216-444-8526 · kwond@ccf.org
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| Cleveland Clinic | Cleveland, Ohio, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06780241