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Study identifier: NCT06779110 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Intracoronary Optical Coherence Tomography Guidance Vs. Angiography Only Guidance for Treatment of Coronary In-stent Restenosis

Condition: Coronary Artery Disease · Stent Restenosis · STENT  ·  Sponsor: San Luigi Gonzaga Hospital

PhaseNA
Planned participants360
Who can joinAll sexes, 18 Years to 99 Years
Healthy volunteersNo

About this study

Although advances in drug-eluting stents (DES) have substantially reduced the risk of coronary in-stent restenosis (ISR) and the need for target lesion revascularisation (TLR), ISR persists. There are several treatment options for ISR (conventional balloon angioplasty, cutting or scoring balloons, drug-coated balloons, repeat DES implantation or bypass surgery). Coronary imaging is mandatory to perform PCI on ISR. Optimal coherence tomography (OCT) is an excellent option to guide PCI, but its role in ISR-PCI remains unclear. The INSIDE OCT Trial aims to compare the acute performance of PCI for ISR, either guided by OCT and angiography or by angiography alone.

This description comes directly from the study's public registry record.

Talk to the study team

Enrico Cerrato, MD, PhD  ·  +393479317104  ·  enricocerrato@gmail.com

Always discuss trial participation with your own doctor first.

Locations (12)

Osp AostaAosta, Aosta, ItalyRecruiting
BiellaBiella, Biella, ItalyRecruiting
Osp. S. Croce e CarleCuneo, Cuneo, ItalyRecruiting
Ospedale Universitario di FerraraCona, Ferrara, ItalyRecruiting
Osp Universitario S. MarinoGenova, Genova, ItalyRecruiting
Infermi Hospital, Rivoli ASLTO3Rivoli, Italy, ItalyRecruiting
Ospedale di TrapaniTrapani, Trapani, ItalyRecruiting
AOU San Luigi GonzagaOrbassano, Turin, ItalyRecruiting
AO MaurizianoTurin, Turin, ItalyRecruiting
AOU Città della Salute e della ScienzaTurin, Turin, ItalyRecruiting
Osp. Giovanni BoscoTurin, TURIN, ItalyRecruiting
Osp VercelliVercelli, Vercelli, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT06779110