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Study identifier: NCT06778811 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Clinical Study of Perioperative Sleep Disorders in Cardiac Surgery

Condition: Sleep Wake Disorders · Esketamine and the Quality of Recovery · Dexmedetomidine  ·  Sponsor: Nanjing First Hospital, Nanjing Medical University

PhasePhase 4
Planned participants180
Who can joinAll sexes, 40 Years to 75 Years
Healthy volunteersNo

About this study

The aim of this clinical trial is to understand the effects of dexmedetomidine and esketamine on postoperative sleep in patients undergoing cardiac surgery. The main questions it aims to answer are: Does dexmedetomidine or esketamine prevent the development of postoperative sleep disturbances? Which one works better? The researchers compared dexmedetomidine and esketamine with saline (a drug-free solvent) to see if dexmedetomidine and esketamine prevented the development of postoperative sleep disturbances. Participants will: 1. Intraoperative continuous infusion of dexmedetomidine, esketamine or saline until the end of surgery 2. Postoperative sleep was assessed on the first and third postoperative days using a sleep rating scale

This description comes directly from the study's public registry record.

Talk to the study team

Kuang xueyi  ·  86+18651908072  ·  kxy809707496@126.com

hongwei shi  ·  86+18951670892  ·  mdshw@163.com

Always discuss trial participation with your own doctor first.

Locations (2)

Nanjing First Hospital,Nanjing Medical UniversityNanjing, Jiangsu, ChinaNot Yet Recruiting
Nanjing First HospitalNanjing, Jiangsu, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06778811