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Study identifier: NCT06778447 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Clinical Trial Evaluating the Safety and Efficacy of Nucleus Pulposus Allograft in Participants With Degenerative Disc Disease

Condition: Degenerative Disc Disease · Disc Degeneration · Lumbar Discogenic Pain  ·  Sponsor: VIVEX Biologics, Inc.

PhaseNA
Planned participants496
Who can joinAll sexes, 22 Years to 85 Years
Healthy volunteersNo

About this study

VIA Disc NP is a non-surgical intervention intended to supplement nucleus pulposus tissue in degenerated intervertebral discs. This is a randomized, sham-controlled, multi-center, double-blind clinical trial with an open label roll-in period of one participant per site in which participants with lumbar discogenic pain associated with DDD will receive one VIA Disc NP treatment to each affected level (up to 2 levels). Participants enrolled after the roll-in stage will be randomized on a 2:1 basis to receive either a single VIA Disc NP intradiscal injection at 1 or 2 levels or the sham procedure at 1 or 2 levels. At 12 months, participants in the sham arm with continued symptoms may cross-over, receive VIA Disc NP, and will restart the study visit schedule, completing an additional 12 months of follow-up post-cross-over.

This description comes directly from the study's public registry record.

Talk to the study team

Leslie Zaccari  ·  714-366-6457  ·  lzaccari@vivex.com

Always discuss trial participation with your own doctor first.

Locations (19)

Interventional Pain Management Napa Valley Orthopedic Medical GroupNapa, California, United StatesRecruiting
Source HealthcareSanta Monica, California, United StatesRecruiting
Premier Spine and Pain InstituteThornton, Colorado, United StatesRecruiting
The Orthopaedic InstituteGainesville, Florida, United StatesRecruiting
Georgia Pain ManagementWoodstock, Georgia, United StatesRecruiting
Henry Community HealthNew Castle, Indiana, United StatesRecruiting
University of KansasKansas City, Kansas, United StatesRecruiting
University of KentuckyLexington, Kentucky, United StatesRecruiting
Ochsner Clinic FoundationNew Orleans, Louisiana, United StatesRecruiting
Spine Institute of LouisianaShreveport, Louisiana, United StatesRecruiting
Paradigm Health SystemSlidell, Louisiana, United StatesRecruiting
Nevada Advanced Pain SpecialistsReno, Nevada, United StatesRecruiting

+ 7 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06778447