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Study identifier: NCT06777979 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

CD19-CD22-Bispecific Chimeric Antigen Receptor (CAR) T Cell Therapy for Pediatric Patients With Acute Lymphoblastic Leukemia

Condition: Acute Lymphoblastic Leukemia · Recurrent Acute Lymphoblastic Leukemia · Recurrent B Acute Lymphoblastic Leukemia  ·  Sponsor: St. Jude Children's Research Hospital

PhasePhase 1
Planned participants30
Who can joinAll sexes, N/A to 21 Years
Healthy volunteersNo

About this study

This study is a phase I study designed to evaluate the safety of CD19-CD22-CAR T cells. Primary Objective: To determine the safety profile and propose the recommended phase 2 dose (RP2D) of autologous CD19-CD22-CAR T cells in patients ≤ 21 years of age with recurrent/refractory CD19- and/or CD22-positive leukemia. Secondary Objective: To evaluate the anti-leukemic activity of CD19-CD22-CAR T cells.

This description comes directly from the study's public registry record.

Talk to the study team

Rebecca Epperly, MD  ·  888-226-4343  ·  referralinfo@stjude.org

Always discuss trial participation with your own doctor first.

Locations (1)

St. Jude Children's Research HospitalMemphis, Tennessee, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06777979