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Study identifier: NCT06777394 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Effects of High Intensity Interval Training in Down Syndrome

Condition: Down Syndrome  ·  Sponsor: Riphah International University

PhaseNA
Planned participants30
Who can joinAll sexes, 3 Years to 14 Years
Healthy volunteersNo

About this study

Down Syndrome (DS), a genetic condition marked by the presence of an extra chromosome 21, is associated with various cognitive and physical challenges. Children with DS often experience motor development issues, including reduced endurance and decreased trunk stability, which underscores the need for targeted interventions. Common impairments in individuals with DS include hypotonia, ligament laxity, reduced muscle strength, limited muscle co-contraction, poor postural control, and impaired proprioception. This study is driven by a lack of research on the effects of High-Intensity Interval Training (HIIT) in this population, despite its documented benefits in enhancing cardiovascular fitness across other groups. Existing literature supports the benefits of exercise interventions for people with DS, but the application and advantages of HIIT-particularly concerning endurance and trunk stability-are underexplored.

This description comes directly from the study's public registry record.

Talk to the study team

Imran Amjad, PhD  ·  033224390125  ·  imranamjad@riphah.edu.pk

Muhammad Aif Javed, MS  ·  03224209422  ·  a.javed@riphah.edu.pk

Always discuss trial participation with your own doctor first.

Locations (1)

Riphah international UniversityLahore, Punjab Province, PakistanRecruiting

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Source record: clinicaltrials.gov/study/NCT06777394