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Study identifier: NCT06776042 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Upper Airway Inflammation and Olfaction: Mechanisms of Loss and Recovery

Condition: Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)  ·  Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain

PhaseNA
Planned participants140
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersYes

About this study

The goal of this clinical trial is to understand the mechanisms leading to olfactory dysfunction (OD) in chronic rhinosinusitis (CRS). The main questions it aims to answer are: * Is the type 2 inflammation impacting the olfactory epithelium regeneration, leading to OD? * Does a treatment interfering with one of the major T2 inflammatory cytokines, have an impact on the mechanisms of OD in CRS? Participants will undergo olfactory testing and nasal brushing before and after 3 months of treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Valérie Hox, MD, PhD  ·  +3227648675  ·  valerie.hox@saintluc.uclouvain.be

Always discuss trial participation with your own doctor first.

Locations (1)

Cliniques Universitaires Saint-LucBrussels, BelgiumRecruiting

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Source record: clinicaltrials.gov/study/NCT06776042