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Study identifier: NCT06775496 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Life-threatening Infection in Humans: from Epidemiological Analysis to Molecular Genetics

Condition: Life-threatening Infection  ·  Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna

PhaseN/A
Planned participants360
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

This study, aims to identify and calculate the prevalence of cases potentially associated with congenital errors of immunity (ECI) among patients, hospitalized with infectious disease and carry out their clinical-laboratory characterization. Diagnoses of ECI are becoming increasingly common, by virtue of the continuing discoveries of new disease-causing genes and an increasing understanding of the clinical signs and symptoms of these entities. The most important challenge still remains to achieve early diagnosis, which is essential for appropriate and individualized treatment that also takes into account the prognostic and genetic counseling aspect related to these disorders, which are associated with high rates of morbidity and mortality. Patients with nonimmunological diseases, secondary immunodeficiencies, nonpharmacological iatrogenic factors, and immunosuppressive drug therapies will be involved in the study.

This description comes directly from the study's public registry record.

Talk to the study team

Daniele Zama, MD  ·  0512144688  ·  daniele.zama2@unibo.it

Always discuss trial participation with your own doctor first.

Locations (6)

IRCCS Istituto delle Scienze NeurologicheBologna, Bologna, ItalyRecruiting
IRCCS Azienda Ospedaliero Universitaria di Bologna UO PediatriaBologna, Bologna, ItalyRecruiting
IRCCS Azienda-Ospedaliero Universitaria di Bologna UO Anestesiologia e Rianimazione generale e pediatricaBologna, Bologna, ItalyRecruiting
IRCCS Azienda-Ospedaliero Universitaria di Bologna UO Malattie InfettiveBologna, Bologna, ItalyRecruiting
IRCCS Azienda-Ospedaliero Universitaria di Bologna UO Neonatologia e terapia intensiva neonataleBologna, Bologna, ItalyRecruiting
IRCCS Azienda-Ospedaliero Universitaria di Bologna UO Pediatria d'Urgenza, Pronto Soccorso e Osservazione Breve e IntensivaBologna, Bologna, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT06775496