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Study identifier: NCT06774872 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Doravirine/Lamivudine (DOR/3TC) as a Maintenance ART in Comparison With Dolutegravir/Lamivudine (DTG/3TC) in PLWH Successfully

Condition: HIV-1-infection  ·  Sponsor: Centre de Recherches et d'Etude sur la Pathologie Tropicale et le Sida

PhasePhase 2
Planned participants408
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The main objective of the MODULO trial is to compare (non-inferiority) the capacity of DOR/3TC and DTG/3TC two-drug regimens of maintain virological success at W48 in people living with HIV virus ( PLWH) with suppressed HIV plasma viral load (pVL) under three-drug regimen at inclusion. The virological success is defined as no virological failure (2 consecutive pVL ≥50 copies/mL or one pVL ≥50 copies/mL followed with discontinuation of treatment or follow-up).

This description comes directly from the study's public registry record.

Talk to the study team

Yasmine DUDOIT  ·  +33 (0)142164181  ·  yasmine.dudoit@aphp.fr

Romain PALICH, MD  ·  +33 (0)142160171  ·  romain.palich@aphp.fr

Always discuss trial participation with your own doctor first.

Locations (1)

Hôpital Pitié-SalpêtrièreParis, Île-de-France Region, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT06774872