Condition: Myopia · Sponsor: Singapore Eye Research Institute
This observational study aims to compare two laser corrective procedures for treating myopia and myopic astigmatism: a novel refractive technique, the CLEAR procedure, and the established SMILE procedure. Participants will be randomized to undergo CLEAR in one eye and SMILE in the other. The investigators will evaluate and compare the two procedures based on the following aspects: refractive predictability (how accurate the vision correction is) by measuring the proportion of eyes close to the target prescription after surgery, clinical dry eye outcomes, changes in tear proteins, and corneal nerve changes at 1, 3, 6, and 12 months after both surgeries. Metabolomic features of the removed corneal tissue and how precisely the laser is centered during surgery will also be examined. Our hypothesis is that CLEAR provides equally good vision results as SMILE, and explore any extra benefits of CLEAR.
This description comes directly from the study's public registry record.
Jodhbir S Mehta, MD, FRCS · 6322 7478 · jodhbir.s.mehta@singhealth.com.sg
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| Singapore National Eye Centre | Singapore, Singapore | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06774651