Condition: Sustained Immunosuppression · Sponsor: University Hospital, Limoges
The goal of this clinical trial is to demonstrate the benefit of a standardized immunotherapy (Interferon gamma) on the incidence of secondary infections. . It will also learn about the safety of Interferon-gamma. The main questions it aims to answer are: Does Interferon-gamma: * reduces the Incidence of secondary infection episodes at three months * reduces the ICU mortality and at Day 90 * reduces the ICU and hospital length of stay * induces Biological immune restoration at Day 10 * has cost-consequence and cost-effectiveness Researchers will compare Interferon-gamma to a placebo (a look-alike substance that contains no drug) to see if Interferon-gamma works to treat sustained immunosuppression . Participants will: * Take Interferon-Gamma or a placebo for a maximum of 5 times between day 1 and day 9 * be monitored evety day until their ICU discharge and at day 30, 60 and 90
This description comes directly from the study's public registry record.
Contact details are listed per location below or on the registry record.
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| Angers university hospial | Angers, France | Recruiting |
| Argenteuil hospital | Argenteuil, France | Recruiting |
| Franche-comté north Hospital | Belfort, France | Recruiting |
| Brive Hospital | Brive-la-Gaillarde, France | Recruiting |
| Chalon sur saone Hospital | Chalon-sur-Saône, France | Recruiting |
| Dijon University Hospital | Dijon, France | Recruiting |
| APHP - Raymond Poincaré | Garches, France | Recruiting |
| Versailles Hospital | Le Chesnay, France | Recruiting |
| Le mans Hospital | Le Mans, France | Recruiting |
| CH de Lens | Lens, France | Recruiting |
| Limoges University Hospital | Limoges, France | Recruiting |
| Lyon Civils Hospices | Lyon, France | Not Yet Recruiting |
+ 11 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06774235