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Study identifier: NCT06774053 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Swiss ProspectivE Cohort of TRAnsgender and Gender Diverse Individuals - The SPECTRA Study

Condition: Transgender Individuals · Gender Incongruence  ·  Sponsor: University Hospital, Basel, Switzerland

PhaseN/A
Planned participants600
Who can joinAll sexes, 16 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this observational study is to understand the factors influencing the well-being and health of transgender and gender-diverse (TGD) individuals undergoing gender-affirming therapies in Switzerland. The study population includes TGD individuals aged 16 and older, at various stages of their medical transition, including those who have discontinued or detransitioned. The main question is: What are the key factors influencing the well-being and health outcomes of transgender and gender-diverse individuals undergoing gender-affirming therapies? Researchers will compare health outcomes across different subgroups, such as those at different stages of transition or detransition, to examine the effects of gender-affirming therapies. Participants will: Complete electronic questionnaires assessing gender congruence, quality of life, mental health, and other outcomes. Provide biological samples (e.g., blood, urine, stool, and skin swabs) for laboratory analysis. Undergo clinical evaluations related to endocrinology, fertility, dermatology, and urology as part of their routine follow-up.

This description comes directly from the study's public registry record.

Talk to the study team

Bettina Winzeler, PD Dr.  ·  +41 61 556 50 75  ·  bettina.winzeler@usb.ch

Hüseyin Cihan, Dr.  ·  hueseyin.cihan@usb.ch

Always discuss trial participation with your own doctor first.

Locations (3)

University Hospital of BaselBasel, SwitzerlandRecruiting
Cantonal Hospital of LucerneLucerne, SwitzerlandNot Yet Recruiting
University Hospital of ZürichZurich, SwitzerlandNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06774053