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Study identifier: NCT06773910 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

BMS-986489 (Atigotatug + Nivolumab) vs Durvalumab in Limited-stage Small-cell Lung Cancer (TIGOS-LS)

Condition: Limited Stage Small Cell Lung Cancer  ·  Sponsor: SCRI Development Innovations, LLC

PhasePhase 2
Planned participants250
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is an open-label, randomized study of BMS-986489 (atigotatug + nivolumab fixed-dose combination) vs durvalumab in limited-stage (LS)-small-cell lung cancer (SCLC) participants. The main goals of this study are to: * Evaluate the efficacy of BMS-986489 vs durvalumab * Evaluate the safety profile of BMS-986489

This description comes directly from the study's public registry record.

Talk to the study team

Sarah Cannon Development Innovations, LLC  ·  1-844-710-6157  ·  SCRI.InnovationsMedical@scri.com

Always discuss trial participation with your own doctor first.

Locations (33)

Southern Cancer CenterDaphne, Alabama, United StatesRecruiting
Sansum ClinicSanta Barbara, California, United StatesRecruiting
Florida Cancer Specialists - SouthFort Myers, Florida, United StatesRecruiting
University of Miami - Sylvester Cancer CenterMiami, Florida, United StatesActive Not Recruiting
Ocala Oncology CenterOcala, Florida, United StatesRecruiting
Florida Cancer Specialists - NorthOrange City, Florida, United StatesRecruiting
Cancer Care Centers of BrevardPalm Bay, Florida, United StatesRecruiting
Florida Cancer Specialists - EastWest Palm Beach, Florida, United StatesRecruiting
Piedmont Healthcare - AtlantaAtlanta, Georgia, United StatesRecruiting
Illinois Cancer SpecialistsArlington Heights, Illinois, United StatesRecruiting
Illinois Cancer CarePeoria, Illinois, United StatesRecruiting
Indiana University Simon Cancer CenterIndianapolis, Indiana, United StatesRecruiting

+ 21 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06773910