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Study identifier: NCT06773195 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of Ruxolitinib in Combination With Ulixertinib in People With Myelofibrosis

Condition: Myelofibrosis  ·  Sponsor: Memorial Sloan Kettering Cancer Center

PhasePhase 1/Phase 2
Planned participants37
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The researchers are doing this study to find out whether the combination of ruxolitinib and ulixertinib is a safe and effective treatment for people with myelofibrosis. The researchers will test different doses of ulixertinib to find the highest dose that causes few or mild side effects in participants when given in combination with ruxolitinib.

This description comes directly from the study's public registry record.

Talk to the study team

Raajit Rampal, MD, PhD  ·  646-608-3746  ·  rampalr@mskcc.org

Prioty Islam, MD, MS  ·  646-608-4273

Always discuss trial participation with your own doctor first.

Locations (9)

Massachusetts General Hospital (Data Collection Only)Boston, Massachusetts, United StatesRecruiting
Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)Basking Ridge, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Monmouth (Limited Protocol Activities)Middletown, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Bergen (Limited Protocol Activities)Montvale, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities)Commack, New York, United StatesRecruiting
Memorial Sloan Kettering Westchester (Limited Protocol Activities)Harrison, New York, United StatesRecruiting
Memorial Sloan Kettering Cancer CenterNew York, New York, United StatesRecruiting
Memorial Sloan Kettering Nassau (Limited Protocol Activities)Uniondale, New York, United StatesRecruiting
Cleveland ClinicCleveland, Ohio, United StatesNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06773195