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Study identifier: NCT06772441 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Artificial Intelligence Driven Personalisation of Radiotherapy and Concomitant Androgen Deprivation Therapy for Prostate Cancer Patients (the HypoPro Trial)

Condition: Prostate Cancer  ·  Sponsor: German Oncology Center, Cyprus

PhasePhase 2
Planned participants30
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

The aim of this prospective, single-arm phase II study is the individualization of both radiotherapy (RT) and androgen deprivation therapy (ADT) duration for patients with high-risk localized prostate cancer (PCa) according to the National Comprehensive Cancer Network (NCCN) based on multimodal artificial intelligence (MMAI) classification. All patients will receive (i) a dose escalation to the prostate via HDR brachytherapy (boost), (ii) twelve months of ADT and (iii) extremely hypofractionated RT to the prostate (5 fractions). This way, patients in the HypoPro trial will receive a prostate-only dose escalation and benefit from shortening of the ADT compared with current guideline recommendations.

This description comes directly from the study's public registry record.

Talk to the study team

Elena Pallari, PhD  ·  +357 25028690  ·  elena.pallari@goc.com.cy

Kristis Vevis, PhD  ·  +357 25208159  ·  kristis.vevis@goc.com.cy

Always discuss trial participation with your own doctor first.

Locations (1)

German Oncology CenterLimassol, CyprusRecruiting

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Source record: clinicaltrials.gov/study/NCT06772441