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Study identifier: NCT06768164 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Quality of Life After Billroth II or Roux-en-Y for Gastric Cancer

Condition: Gastric (Cardia, Body) Cancer  ·  Sponsor: Assistance Publique - Hôpitaux de Paris

PhasePhase 3
Planned participants250
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The treatment of a local distal gastric cancer remains surgical before or after chemotherapy. Partial gastrectomy is recommended for distal location cancer The recommendations for restoring continuity are less evident. There are two main techniques: the Roux-En-Y (REY) requiring 2 anastomoses (gastro-jejunostomy and entero-enterostomy) and the Billroth 2 (B2) with a single anastomosis (gastro-jejunostomy). The choice remains matter of debate. There was no difference on the global health status score from the QLQ-C30 questionnaire. However, the health-related quality of life (HRQoL) was significantly improved only in the REY group between pre- and post-gastrectomy. A significant difference for endoscopic gastritis in favor of the REY group was reported. The purpose of this study is to determine which surgical technique improve the health related quality of life after distal gastrectomy.

This description comes directly from the study's public registry record.

Talk to the study team

Alexandre CHALLINE, MD, PhD  ·  +33 1 49 28 25 33  ·  alexandre.challine@aphp.fr

Christelle AUGER  ·  +33 1 58 41 11 86  ·  christelle.auger@aphp.fr

Always discuss trial participation with your own doctor first.

Locations (1)

Hôpital Saint-AntoineParis, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT06768164