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Study identifier: NCT06765941 Synced from ClinicalTrials.gov · July 28, 2026
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PTeye vs Surgeons Eyes in Intraoperative Identification and Functional Preservation of Parathyroid Glands During Thyroid Surgery: A Parallel Randomized Controlled Clinical Trial.

Condition: Thyroid Surgery · Parathyroid Dysfunction · Hypoparathyroidism Post-surgical  ·  Sponsor: Marcin Barczynski

PhaseNA
Planned participants154
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this randomized clinical trial is to learn if there are any added benefits of using near-infrared autofluorescence (NIRAF) probe-based imaging system (the PTeye) for intraoperative identification of parathyroid glands (PGs) during thyroid surgery in comparison to visual identification of PGs by the surgeon's naked eyes without PTeye. The main questions it aims to answer are: * Is number of PGs identified intraoperatively and preserved in situ larger in thyroid operations with PTeye versus surgeon's naked eyes without PTeye? * Is number of patients with undetectable or low parathormone serum level on postoperative day 1 fewer in thyroid operations with PTeye versus surgeon's naked eyes without PTeye? * Is number of patients requiring substitution therapy with calcium and vitamin D analogue fewer after thyroid operations with PTeye versus surgeon's naked eyes without PTeye in a short-term (\< 6 weeks) and/or in a long-term (at 6 months) follow-up? * Is numer of inadvertenly removed and reimplanted PGs fewer in thyroid operations with PTeye versus surgeon's naked eyes without PTeye? * Is number of frozen sections fewer in thyroid operations with PTeye versus surgeon's naked eyes without PTeye? * Is number of PGs identified by pathologist in the surgical specimen fewer in in thyroid operations with PTeye versus surgeon's naked eyes without PTeye? * Is number of patients with symptomatic hypoparathyroidism within 30 days of the operation fewer in thyroid operations w…

This description comes directly from the study's public registry record.

Talk to the study team

Marcin Barczyński, MD, PhD  ·  48123516663  ·  marbar@mp.pl

Aleksander Konturek, MD, PhD  ·  48123516663  ·  okont@mp.pl

Always discuss trial participation with your own doctor first.

Locations (1)

Department of Endocrine Surgery, Faculty of Medicine, Jagiellonian University Medical CollegeKrakow, Małopolska, PolandRecruiting

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Source record: clinicaltrials.gov/study/NCT06765941