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Study identifier: NCT06765317 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of Glofitamab-based Treatment in People With Diffuse Large B-cell Lymphoma

Condition: Diffuse Large B Cell Lymphoma (DLBCL) · High Grade B Cell Lymphoma  ·  Sponsor: Memorial Sloan Kettering Cancer Center

PhasePhase 2
Planned participants42
Who can joinAll sexes, 65 Years to 80 Years
Healthy volunteersNo

About this study

The researchers are doing this study to find out if the study treatment is an effective treatment that causes few or mild side effects in people with diffuse large B-cell lymphoma (DLBCL), high-grade B-cell lymphoma (HGBCL), or transformed lymphoma. The treatment being tested in this study is glofitamab, polatuzumab, and obinutuzumab in combination with standard treatment (the combination of rituximab, cyclophosphamide, doxorubicin, and prednisone, or R-miniCHP).

This description comes directly from the study's public registry record.

Talk to the study team

Pallawi Torka, MD  ·  201-775-7808  ·  torkap@mskcc.org

Paul Hamlin, MD  ·  646-608-3706

Always discuss trial participation with your own doctor first.

Locations (8)

Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)Basking Ridge, New Jersey, United StatesRecruiting
Hackensack Meridian Health (Data collection only)Hackensack, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Monmouth (Limited Protocol Activities)Middletown, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Bergen (Limited Protocol Activities)Montvale, New Jersey, United StatesRecruiting
Memorial Sloan Kettering Cancer Center Suffolk - Commack (Limited Protocol Activities)Commack, New York, United StatesRecruiting
Memorial Sloan Kettering Westchester (All Protocol Activities)Harrison, New York, United StatesRecruiting
Memorial Sloan Kettering Cancer Center (All Protocol Activities)New York, New York, United StatesRecruiting
Memorial Sloan Kettering Nassau (Limited Protocol Activities)Rockville Centre, New York, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06765317