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Study identifier: NCT06763536 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Oral Nicotine Pouches Versus Nicotine Replacement Therapy to Reduce Cigarette Use for Smokers in Rural Appalachia

Condition: Cigarette Smoking-Related Carcinoma  ·  Sponsor: Ohio State University Comprehensive Cancer Center

PhaseNA
Planned participants1000
Who can joinAll sexes, 21 Years to no upper limit
Healthy volunteersYes

About this study

This clinical trial compares the use of oral nicotine pouches to nicotine replacement therapy, consisting of nicotine patches and lozenges, to reduce cigarette use in smokers living in rural Appalachia. The lung and oral cancers that plague Appalachia are fueled by cigarette smoking. Oral nicotine pouches which contain nicotine but no tobacco leaf, present a new opportunity to reduce cancer risk among Appalachian adults who smoke. Oral nicotine pouches and nicotine replacement therapy may work well to reduce cigarette use for smokers in rural Appalachia.

This description comes directly from the study's public registry record.

Talk to the study team

The Ohio State University Comprehensive Cancer Center  ·  800-293-5066  ·  OSUCCCClinicaltrials@osumc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Ohio State University Comprehensive Cancer CenterColumbus, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06763536